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Article

Preferential rearrangements of the T cell receptor-delta-deleting elements in human T cells.

Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 1997

Verschuren M C, Wolvers-Tettero I L, Breit T M, Noordzij J, van Wering E R, van Dongen J J

Abstract excerpt

The major part of the TCR-delta locus is flanked by the so-called TCR-delta-deleting elements deltaRec and psi(J)alpha, which preferentially rearrange to each other in human thymocytes. On the basis of our combined Southern blot and PCR analyses, we also identified the prominent deltaRec-Jalpha58 rearrangement and three other preferential deltaRec rearrangements. The latter rearrangements concern deltaRec...

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PMID: 9013961

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