Interleukin 2-independent interleukin 7 activity enhances cytotoxic immune response of HIV-1-infected individuals.

doi:10.1089/aid.1994.10.121

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Article

Interleukin 2-independent interleukin 7 activity enhances cytotoxic immune response of HIV-1-infected individuals.

AIDS research and human retroviruses - 1 Feb 1994

Carini C, Essex M

Abstract excerpt

Virus-specific cytotoxic T lymphocytes (CTLs), which kill virus-infected cells, are thought to be a major host defense against viral infections. The addition of interleukin 7 (IL-7) at the onset of mitogen-stimulated cultures resulted in a marked (up to threefold) augmentation of env-specific cyt...

Topics

Adult
Cell Line, Transformed
Cytotoxicity, Immunologic
Epitopes
HIV Antigens
HIV Infections
HIV-1
Humans
Interleukin-2
Interleukin-7
Lymphocyte Activation
Middle Aged
Monocytes
Phenotype
Recombinant Proteins
T-Lymphocytes, Cytotoxic
Time Factors

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