Article
Regulatory effects of interleukin-7 on renal tumor infiltrating lymphocytes.
Urological research - 1 Jan 1992
Ditonno P, Tso C L, Sakata T, deKernion J B, Belldegrun A
Abstract excerpt
Biological therapy using a combination of lymphokine and tumor infiltrating lymphocytes (TILs) is a new approach to the treatment of patients with advanced cancer. To improve the potency of TILs, new cytokines with T-cell stimulatory effects used alone or in combination with interleukin-2 (IL-2) are currently being investigated. We have studied the effect of interleukin-7 (IL-7) on TILs derived from renal cell...
Topics
- Antigens, CD
- Carcinoma, Renal Cell
- Drug Synergism
- Humans
- Immunotherapy
- In Vitro Techniques
- Interleukin-2
- Interleukin-7
- Kidney Neoplasms
- Lymphocyte Activation
- Lymphocytes, Tumor-Infiltrating
