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Article

IL-7 is a potent and proviral strain–specific inducer of latent HIV-1 cellular reservoirs of infected individuals on virally suppressive HAART

2005-01-03

Abstract excerpt

The persistence of HIV-1 in virally suppressed infected individuals on highly active antiretroviral therapy (HAART) remains a major therapeutic problem. The use of cytokines has been envisioned as an additional therapeutic strategy to stimulate latent proviruses in these individuals. Immune activation therapy using IL-2 has shown some promise. In the present study, we found that IL-7 was significantly more effecti...

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Identifiers and source

Literature Corpus work
f1a33ecd-7f3e-5065-bff9-4087a044a254
DOI
10.1172/jci200522574
Open publication

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IL-7 is a potent and proviral strain–specific inducer of latent HIV-1 cellular reservoirs of infected individuals on virally suppressive HAARTDOI 10.1172/jci200522574
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