Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dysregulation of interleukin‐7 receptor may generate loss of cytotoxic T cell response in human immunodeficiency virus type 1 infection

1 Dec 1994

Abstract excerpt

Virus-specific cytotoxic T lymphocytes (CTL) play a crucial role in modulating an immune response against human immunodeficiency type 1 (HIV-1) infection. The generation of effector cytotoxic cells from CTL precursors involves intricate interactions with antigen via T cell receptors (TcR) and soluble cytokines. Interleukin (IL)-7 can affect T cell maturation and differentiation. Here we report on a group of five...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS Research and Interventions
Share to HIV Research and Treatment
Share to Immune Cell Function and Interaction

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7805718
DOI: 10.1002/eji.1830241202

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dysregulation of interleukin‐7 receptor may generate loss of cytotoxic T cell response in human immunodeficiency virus type 1 infectionPMID 7805718Read ↗

Interleukin 2-independent interleukin 7 activity enhances cytotoxic immune response of HIV-1-infected individuals.Semantic proximity Read ↗

Genetic Manipulation of Tumor-specific Cytotoxic T Lymphocytes to Restore Responsiveness to IL-7Semantic proximity Read ↗

A partial deficiency of interleukin-7R alpha is sufficient to abrogate T-cell development and cause severe combined immunodeficiency.Semantic proximity Read ↗

Differential Regulation of Human IL-7 Receptor α Expression by IL-7 and TCR SignalingSemantic proximity Read ↗

Modulation of interleukin-7 receptor expression characterizes differentiation of CD8 T cells specific for HIV, EBV and CMVSemantic proximity Read ↗

Interleukin 7 reduces the levels of spontaneous apoptosis in CD4 <sup>+</sup> and CD8 <sup>+</sup> T cells from HIV-1-infected individualsSemantic proximity Read ↗

IL7RA single nucleotide polymorphisms are associated with the size and function of the MAIT cell population in treated HIV-1 infection.Semantic proximity Read ↗

IL-7 receptor is expressed on adult pre-B-cell acute lymphoblastic leukemia and other B-cell derived neoplasms and correlates with expression of proliferation and survival markers.Semantic proximity Read ↗

Interleukin-7 promotes HIV persistence during antiretroviral therapy.Semantic proximity Read ↗

Effects of exogenous interleukin-7 on human thymus functionSemantic proximity Read ↗

Recombinant interleukin-7 induces proliferation of naive macaque CD4+ and CD8+ T cells in vivo.Semantic proximity Read ↗

The human IL-7 receptor gene: deletions, polymorphisms and mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.