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Article

Recombinant interleukin-7 induces proliferation of naive macaque CD4+ and CD8+ T cells in vivo.

Journal of virology - 1 Sept 2004

Moniuszko Marcin, Fry Terry, Tsai Wen-Po, Morre Michel, Assouline Brigitte, Cortez Pierre, Lewis Mark G, Cairns Scott, Mackall Crystal, Franchini Genoveffa

Abstract excerpt

Interleukin-7 (IL-7) regulates T-cell homeostasis, and its availability is augmented in lymphopenic hosts. Naive CD8+ T cells transferred to lymphopenic mice acquire a memory-like phenotype, raising the possibility that IL-7 is the biological mediator of this effect. Here, we provide direct evidence that IL-7 induces the acquisition of memory-cell markers not only in CD8+ T cells but also in CD4+ T-cell subsets...

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Source

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Identifiers

PMID: 15331707
DOI: 10.1128/JVI.78.18.9740-9749.2004
PMCID: PMC515001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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