Article
The pleiotropic effects of interleukin 7 and their pathologic and therapeutic implications.
The European journal of medicine - 1 May 1992
Costello R, Duffaud F
Abstract excerpt
Interleukin-7 (IL-7) is a cytokine initially described as a growth factor for B cell progenitors. IL-7 also induces T cell proliferation and has pleiotropic effects. IL-7 enhances T-lymphocyte cytotoxicity, stimulates anti-tumoural properties of monocytes/macrophages, and induces tumour rejection in mice. It could thus be of interest in immunotherapy and may play a role in the generation of lymphoid neoplasia...
Topics
- Animals
- B-Lymphocytes
- Cell Division
- Humans
- Immunotherapy, Adoptive
- Interleukin-7
- Lymphoma
- Phenotype
- Stem Cells
- T-Lymphocytes