Article
Hypervariable region IV of Salmonella gene fliCd encodes a dominant surface epitope and a stabilizing factor for functional flagella.
Journal of bacteriology - 1 Apr 1994
He X S, Rivkina M, Stocker B A, Robinson W S
Abstract excerpt
To identify the major antigenic determinant of native Salmonella flagella of antigenic type d, we constructed a series of mutated fliCd genes with deletions and amino acid alterations in hypervariable region IV and in region of putative epitopes as suggested by epitope mapping with synthetic octa...
Topics
- Amino Acid Sequence
- Animals
- Antigens, Bacterial
- Antigens, Surface
- Base Sequence
- Epitopes
- Female
- Flagellin
- Genes, Bacterial
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Mutation
- Recombinant Proteins
- Salmonella