Article
Expression of the thrombospondin receptor (CD36) on the cell surface in megakaryoblastic and promegakaryocytic leukemias: increment of the receptor by megakaryocyte differentiation in vitro.
American journal of hematology - 1 Feb 1994
Imamura N, Ota H, Abe K, Kuramoto A
Abstract excerpt
In this report we describe four cases of acute megakaryocytic leukemia demonstrated by the presence of megakaryocyte-platelet-related cell-surface antigens. These were detected utilizing flow cytometry and monoclonal antibodies in addition to both platelet peroxidase activity, which was shown by...
Topics
- Antigens, CD
- CD36 Antigens
- Cell Differentiation
- Cells, Cultured
- Humans
- Leukemia, Megakaryoblastic, Acute
- Megakaryocytes
- Phenotype
- Platelet Membrane Glycoproteins