Granulocyte Colony-Stimulating Factor Receptor at Various Differentiation Stages of Normal and Leukemic Hematopoietic Cells

Abstract excerpt

Granulocyte colony-stimulating factor (G-CSF) is the most important cytokine in granulopoiesis, and induces the proliferation and differentiation of normal bone marrow granulocytic precursors. The physiologic effect of G-CSF is mediated through binding to specific cell surface receptors for G-CSF. Using a newly-devised quantitative flow-cytometric assay, we analyzed the expression of G-CSF receptors on normal and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Acute Myeloid Leukemia Research
• Share to Blood disorders and treatments
• Share to Chronic Lymphocytic Leukemia Research