Article
Expression of the CD11/CD18, leukocyte adhesion molecule 1, and CD44 adhesion molecules during normal myeloid and erythroid differentiation in humans.
Blood - 15 Dec 1990
Kansas G S, Muirhead M J, Dailey M O
Abstract excerpt
We have used three-color flow cytometry to investigate the pattern of expression of the CD11/CD18, CD44, and leukocyte adhesion molecule 1 (LAM-1) adhesion molecules during myeloid and erythroid differentiation in humans. The earliest myeloid cells, identified as CD33loCD15-, were exclusively CD44hi but contained both leukocyte function-associated antigen 1 (LFA-1hi) and LFA-1lo cells, as well as LAM-1+ and...
Topics
- Antigens, Differentiation
- Bone Marrow
- Bone Marrow Cells
- CD11 Antigens
- CD18 Antigens
- Cell Adhesion Molecules
- Cell Differentiation
- Down-Regulation
- Erythrocytes
- Flow Cytometry
- Gene Expression
