Structure and localization of the IGFBP-1 gene and its expression during liver regeneration

Abstract excerpt

Insulin-like growth factor-binding protein-1s are important modulators of the insulin-like growth factors that may have both positive and negative effects on the ability of insulin-like growth factors to stimulate cell growth. The IGFBP -1 gene is one of the most highly induced immediate-early genes after partial hepatectomy. The IGFBP -1 gene is also expressed at a high level during fetal liver development and...

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