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Article

Gene Expression Profiling Reveals the Mechanism and Pathophysiology of Mouse Liver Regeneration

1 Aug 2003

Abstract excerpt

Comprehensive analysis of the changes in gene expression during liver regeneration was carried out by using an in-house microarray composed of 2,304 distinct mouse liver cDNA clones. Mice were subjected to partial two-thirds hepatectomy, and changes in mRNA levels were monitored up to 48 h. Of the 2,304 genes analyzed, 496 genes showed expression levels measurable at all time points after the partial hepatectomy....

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PMID: 12782638
DOI: 10.1074/jbc.m212648200

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