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Article

Protein tyrosine phosphatase of liver regeneration-1 is required for normal timing of cell cycle progression during liver regeneration.

American journal of physiology. Gastrointestinal and liver physiology - 15 Jan 2015

Jiao Yang, Ye Diana Z, Li Zhaoyu, Teta-Bissett Monica, Peng Yong, Taub Rebecca, Greenbaum Linda E, Kaestner Klaus H

Abstract excerpt

Protein tyrosine phosphatase of liver regeneration-1 (Prl-1) is an immediate-early gene that is significantly induced during liver regeneration. Several in vitro studies have suggested that Prl-1 is important for the regulation of cell cycle progression. To evaluate its function in liver regeneration, we ablated the Prl-1 gene specifically in mouse hepatocytes using the Cre-loxP system. Prl-1 mutant mice...

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Identifiers

PMID: 25377314
DOI: 10.1152/ajpgi.00084.2014
PMCID: PMC4380483

Genes

STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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