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Article

Temporal expression profiles indicate a primary function for microRNA during the peak of DNA replication after rat partial hepatectomy

24 Mar 2011

Abstract excerpt

The liver has the unique capacity to regenerate after surgical resection. However, the regulation of liver regeneration is not completely understood. Recent reports indicate an essential role for small noncoding microRNAs (miRNAs) in the regulation of hepatic development, carcinogenesis, and early regeneration. We hypothesized that miRNAs are critically involved in all phases of liver regeneration after partial...

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PMID: 21430077
DOI: 10.1152/ajpregu.00632.2010

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