Hematopoietic origin of human natural killer (NK) cells: generation from immature progenitors.

doi:10.1159/000163803

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Article

Hematopoietic origin of human natural killer (NK) cells: generation from immature progenitors.

Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 1993

Silva M R, Kessler S, Ascensao J L

Abstract excerpt

Human natural killer (NK) cells originate from bone marrow, but little is known about NK cell progenitors and ontogeny. We studied the phenotype and functional activity of NK cells derived from highly purified human bone marrow CD34+ cells, which exhibited neither lytic activity nor expression of...

Topics

Antigens, CD
Antigens, CD34
Antigens, Differentiation, T-Lymphocyte
Bone Marrow
Bone Marrow Cells
CD3 Complex
CD56 Antigen
Cells, Cultured
Hematopoietic Stem Cells
Humans
Interleukin-2
Killer Cells, Natural
Phenotype
T-Lymphocytes

Source

Open in PubMed

Identifiers

PMID: 7507682
DOI: 10.1159/000163803

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7507682-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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