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Article

Hematopoietic origin of human natural killer (NK) cells: generation from immature progenitors.

Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 1993

Silva M R, Kessler S, Ascensao J L

Abstract excerpt

Human natural killer (NK) cells originate from bone marrow, but little is known about NK cell progenitors and ontogeny. We studied the phenotype and functional activity of NK cells derived from highly purified human bone marrow CD34+ cells, which exhibited neither lytic activity nor expression of surface antigens characteristic of NK (CD56) or T (CD3) cells. However, when cultured with hematopoietic growth...

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Identifiers

PMID: 7507682
DOI: 10.1159/000163803

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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