Article
Isolation and analysis of human natural killer cell subsets.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2008
Ferlazzo Guido
Abstract excerpt
Natural killer (NK) cells were originally defined as mediators of spontaneous cytotoxicity against virus-infected and tumor cells. In human peripheral blood, the majority of NK cells can mediate cell lysis mainly through perforin and granzymes. It has been recently shown, however, that the majority of NK cells in human secondary lymphoid organs are primarily immunoregulatory by secreting cytokines immediately...
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