Article
Human natural killer cell development in secondary lymphoid tissues.
Seminars in immunology - 1 Apr 2014
Freud Aharon G, Yu Jianhua, Caligiuri Michael A
Abstract excerpt
For nearly a decade it has been appreciated that critical steps in human natural killer (NK) cell development likely occur outside of the bone marrow and potentially necessitate distinct microenvironments within extramedullary tissues. The latter include the liver and gravid uterus as well as secondary lymphoid tissues such as tonsils and lymph nodes. For as yet unknown reasons these tissues are naturally...
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