Characterization of the invariant chain C-terminus (Glu183-Glu193) epitope which is obscured in processed Ii, MHC alpha,beta trimers.

doi:10.1016/0161-5890(93)90442-e

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Article

Characterization of the invariant chain C-terminus (Glu183-Glu193) epitope which is obscured in processed Ii, MHC alpha,beta trimers.

Molecular immunology - 1 Dec 1993

Nguyen Q V, Knapp W, Humphreys R E

Abstract excerpt

The E1 serum was developed against invariant chain peptide Ii (183-193) in order to study the function of the Ii protein which associates with class II MHC alpha,beta chains from time of synthesis until cleavage and release, possibly regulating the binding of antigenic peptides. Subpopulations of...

Topics

Antibody Specificity
Antigens, Differentiation, B-Lymphocyte
Cells, Cultured
Epitopes
Genetic Variation
Hexosaminidases
Histocompatibility Antigens Class II
Humans
Neuraminidase
Precipitin Tests
Protein Conformation
Urea

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