Biosynthesis and intracellular transport of MHC class II molecules associated with a mutated, glycosaminoglycan-negative invariant chain.

doi:10.1016/0161-5890(90)90165-v

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Article

Biosynthesis and intracellular transport of MHC class II molecules associated with a mutated, glycosaminoglycan-negative invariant chain.

Molecular immunology - 1 May 1990

Simonis S, Miller J, Cullen S E

Abstract excerpt

The MHC Class II molecular complex is composed of polymorphic alpha and beta chains and a non-polymorphic "invariant" chain (Ii) that can be converted to a chondroitin sulfate proteoglycan. To determine whether the proteoglycan form of invariant chain (Ii-CS) had a role in the expression of the C...

Topics

Animals
Antigens, Surface
Biological Transport
Glycosaminoglycans
Histocompatibility Antigens Class II
Mutation
Protein Processing, Post-Translational
Transfection

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