Genetic and molecular advances in Alzheimer's disease.

doi:10.1016/0166-2236(93)90007-9

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Article

Genetic and molecular advances in Alzheimer's disease.

Trends in neurosciences - 1 Oct 1993

Mullan M, Crawford F

Abstract excerpt

The abnormal deposition of amyloid beta protein (A beta) in the brain is the major neuropathological characteristic of Alzheimer's disease (AD). The disease in some early-onset familial cases develops as a result of mutations in the gene coding for the beta-amyloid precursor protein (beta APP) an...

Topics

Age of Onset
Alzheimer Disease
Amyloid beta-Protein Precursor
Chromosome Mapping
Chromosomes, Human, Pair 14
Chromosomes, Human, Pair 19
Genes
Genetic Linkage
Genetics
Humans
Molecular Biology
Mutation
Neurotoxins

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