Article
[Genetic basis for Alzheimer's disease and other dementias and prospects of molecular diagnosis].
Vestnik Rossiiskoi akademii meditsinskikh nauk - 1 Jan 1999
Rogaev E I
Abstract excerpt
Dementias are diseases of progressive memory loss and intellectual impairment in adults. Alzheimer's disease (AD) amounts to 50-80% of all forms of dementias in middle-aged and elderly individuals. AD includes several clinical and genetic subtypes characterized by the common pattern of specific cerebral hallmarks. Aging and genetic factors are the most important risk factors predisposing to AD. Three gene-bearing...
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