Article
The role of Sse1 in the de novo formation and variant determination of the [PSI+] prion.
Genetics - 1 Nov 2007
Fan Qing, Park Kyung-Won, Du Zhiqiang, Morano Kevin A, Li Liming
Abstract excerpt
Yeast prions are a group of non-Mendelian genetic elements transmitted as altered and self-propagating conformations. Extensive studies in the last decade have provided valuable information on the mechanisms responsible for yeast prion propagation. How yeast prions are formed de novo and what cellular factors are required for determining prion "strains" or variants--a single polypeptide capable of existing in...
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