Article
Mutations in the gene encoding the 34 kDa subunit of yeast replication protein A cause defective S phase progression.
Journal of molecular biology - 8 Dec 1995
Santocanale C, Neecke H, Longhese M P, Lucchini G, Plevani P
Abstract excerpt
The in vivo function of the 34 kDa subunit of yeast replication protein A (RPA), encoded by the RFA2 gene, has been studied by analyzing the effect of Rpa34 depletion and by producing and characterizing rfa2 temperature-sensitive mutants. We show that unbalanced stoichiometry of the RPA subunits...
Topics
- Bacterial Proteins
- Base Sequence
- Cell Cycle
- Cell Cycle Proteins
- Cell Death
- Cell Division
- DNA Polymerase II
- DNA Repair
- DNA Replication
- DNA-Binding Proteins
- Fungal Proteins
- G2 Phase
- Glycosyltransferases
- Molecular Sequence Data
- Mutation
- Plasmids
- Replication Protein A
- Repressor Proteins