Article
Signaling of ambient pH in Aspergillus involves a cysteine protease.
The Journal of biological chemistry - 1 Dec 1995
Denison S H, Orejas M, Arst H N
Abstract excerpt
In Aspergillus nidulans, the regulation of gene expression in response to changes in ambient pH is mediated by the PacC zinc finger transcriptional regulator. At alkaline ambient pH, PacC is proteolytically processed to a functional form serving as an activator of alkaline-expressed genes and a r...
Topics
- Amino Acid Sequence
- Animals
- Aspergillus nidulans
- Base Sequence
- Cysteine Endopeptidases
- Fungal Proteins
- Humans
- Hydrogen-Ion Concentration
- Hydrolysis
- Molecular Sequence Data
- Mutation
- Sequence Homology, Amino Acid
- Signal Transduction