Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular and structural characterization of the heat-resistant thyroxine-binding globulin-Chicago.

The Journal of biological chemistry - 24 Nov 1995

Janssen O E, Chen B, Büttner C, Refetoff S, Scriba P C

Abstract excerpt

Thyroxine-binding globulin (TBG) is the main transport protein for thyroxine (T4) in blood. It shares considerable sequence homology with alpha 1-antitrypsin (AT) and other members of the serine proteinase inhibitor (serpin) superfamily of proteins. The crystallographic structure of AT has been determined and was found to represent the archetype of the serpins. This model has been used for structure-function...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutagenesis, Site-Directed

Share to Recombinant Proteins

Share to Restriction Mapping

Share to Sequence Homology, Amino Acid

Source

Identifiers

PMID: 7499319
DOI: 10.1074/jbc.270.47.28234

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular and structural characterization of the heat-resistant thyroxine-binding globulin-Chicago.PMID 7499319Read ↗

Loop variants of the serpin thyroxine-binding globulin: implications for hormone release upon limited proteolysis.Semantic proximity Read ↗

Characterization of the thyroxine-binding site of thyroxine-binding globulin by site-directed mutagenesis.Semantic proximity Read ↗

C-terminal amino acid alteration rather than late termination causes complete deficiency of thyroxine-binding globulin CD-NeuIsenburg.Semantic proximity Read ↗

An additional carbohydrate chain in the variant thyroxine-binding globulin-Gary (TBGAsn-96) impairs its secretion.Semantic proximity Read ↗

The structure of human thyroglobulin.Semantic proximity Read ↗

Partial deficiency of thyroxine-binding globulin-Allentown is due to a mutation in the signal peptide.Semantic proximity Read ↗

Molecular and structural basis of steroid hormone binding and release from corticosteroid-binding globulin.Semantic proximity Read ↗

The thermal stability of Hb O-Indonesia [alpha 116(GH4)Glu----Lys].Semantic proximity Read ↗

Sequencing of the variant thyroxine-binding globulin (TBG)-San Diego reveals two nucleotide substitutions.Semantic proximity Read ↗

In vitro expression of thyroxine-binding globulin (TBG) variants. Impaired secretion of TBGPRO-227 but not TBGPRO-113.Semantic proximity Read ↗

The role of the conserved COOH-terminal triad in alphaA-crystallin aggregation and functionality.Semantic proximity Read ↗

Molecular basis for the properties of the thyroxine-binding globulin-slow variant in American blacks.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.