Article
Molecular and structural characterization of the heat-resistant thyroxine-binding globulin-Chicago.
The Journal of biological chemistry - 24 Nov 1995
Janssen O E, Chen B, Büttner C, Refetoff S, Scriba P C
Abstract excerpt
Thyroxine-binding globulin (TBG) is the main transport protein for thyroxine (T4) in blood. It shares considerable sequence homology with alpha 1-antitrypsin (AT) and other members of the serine proteinase inhibitor (serpin) superfamily of proteins. The crystallographic structure of AT has been d...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Female
- Genetic Variation
- Genomic Library
- Humans
- Leukocytes
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Oligodeoxyribonucleotides
- Oocytes
- Protein Biosynthesis
- Recombinant Proteins
- Restriction Mapping
- Reticulocytes
- Sequence Homology, Amino Acid
- Thyroxine