Article
Molecular basis for the properties of the thyroxine-binding globulin-slow variant in American blacks.
Journal of endocrinological investigation - 1 Apr 1990
Waltz M R, Pullman T N, Takeda K, Sobieszczyk P, Refetoff S
Abstract excerpt
Thyroxine-binding globulin-slow (TBG-S), a variant found in 4-12% of Black and Pacific Island populations, is inherited as an X-chromosome linked trait. This variant is detected on isoelectric focusing by the characteristic cathodal shift of all its isoforms, suggesting that the difference reside...
Topics
- Amino Acid Sequence
- Asparagine
- Aspartic Acid
- Base Sequence
- Black People
- DNA
- Electrophoresis, Polyacrylamide Gel
- Genetic Variation
- Humans
- Male
- Molecular Sequence Data
- Mutation
- Phenotype
- Thyroxine-Binding Proteins
- United States
- Black or African American