Human cord blood mononuclear cells are preferentially infected by non-syncytium-inducing, macrophage-tropic human immunodeficiency virus type 1 isolates.

doi:10.1128/jcm.33.2.292-297.1995

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Article

Human cord blood mononuclear cells are preferentially infected by non-syncytium-inducing, macrophage-tropic human immunodeficiency virus type 1 isolates.

Journal of clinical microbiology - 1 Feb 1995

Reinhardt P P, Reinhardt B, Lathey J L, Spector S A

Abstract excerpt

Identification of the factors which impact on the transmission of human immunodeficiency virus type 1 (HIV-1) from an infected mother to her infant is essential for the development of effective strategies to prevent perinatal HIV-1 infection. The current study was designed to determine if unstimulated human neonatal cord blood mononuclear cells (CBMC) differ from adult peripheral blood mononuclear cells (PBMC) in...

Topics

Adult
Cytopathogenic Effect, Viral
Female
Fetal Blood
Flow Cytometry
HIV Infections
HIV-1
Humans
In Vitro Techniques
Infant, Newborn
Leukocytes, Mononuclear

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Macrophages

Maternal-Fetal Exchange

Phenotype

Phytohemagglutinins

Pregnancy

Pregnancy Complications, Infectious

Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 7714181
DOI: 10.1128/jcm.33.2.292-297.1995
PMCID: PMC227935

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7714181-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Human cord blood mononuclear cells are preferentially infected by non-syncytium-inducing, macrophage-tropic human immunodeficiency virus type 1 isolates.PMID 7714181Read ↗

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