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Regulation of chondrocyte gene expression by osteogenic protein-1

29 Mar 2011

Abstract excerpt

INTRODUCTION: The objective of this study was to investigate which genes are regulated by osteogenic protein-1 (OP-1) in human articular chondrocytes using Affimetrix gene array, in order to understand the role of OP-1 in cartilage homeostasis. METHODS: Chondrocytes enzymatically isolated from 12 normal ankle cartilage samples were cultured in high-density monolayers and either transfected with OP-1 antisense...

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PMID: 21447156
DOI: 10.1186/ar3300

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