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Article

Steroidogenic factor 1 is the essential transcript of the mouse Ftz-F1 gene.

Molecular endocrinology (Baltimore, Md.) - 1 Sept 1995

Luo X, Ikeda Y, Schlosser D A, Parker K L

Abstract excerpt

Targeted disruption of the mouse Ftz-F1 gene, which encodes the orphan nuclear receptors steroidogenic factor 1 (SF-1) and embryonal long terminal repeat-binding protein (ELP), established that this gene is essential for development of the primary steroidogenic tissues and for male sexual differentiation. Associated with these dramatic developmental abnormalities, all Ftz-F1-disrupted mice died in the immediate...

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PMID: 7491115
DOI: 10.1210/mend.9.9.7491115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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