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Article

The role of steroidogenic factor 1 (SF-1) in steroidogenic cell function of the testes and ovaries of mature mice

4 Oct 2022

Abstract excerpt

In brief: The nuclear receptor steroidogenic factor 1 (SF-1) is essential for mature mouse gonad steroidogenic gene expression, for Leydig and Sertoli cell function, and depletion of SF-1 in steroidogenic cells of the testis compromises steroidogenesis, spermatogenesis and male fertility. Abstract: Steroidogenic factor 1 (SF-1 or NR5A1) plays an essential role in the development of fetal gonads and regulates...

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Identifiers

PMID: 36194434
DOI: 10.1530/rep-22-0049

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The role of steroidogenic factor 1 (SF-1) in steroidogenic cell function of the testes and ovaries of mature micePMID 36194434Read ↗

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Steroidogenic Factor 1 (Nr5a1) is Required for Sertoli Cell Survival Post Sex DeterminationSemantic proximity Read ↗

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Combined Loss of the GATA4 and GATA6 Transcription Factors in Male Mice Disrupts Testicular Development and Confers Adrenal-Like Function in the TestesSemantic proximity Read ↗

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