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Article

Cloning and sequence analysis of the human gene encoding steroidogenic factor 1

1 Oct 1996

Abstract excerpt

The orphan nuclear receptor steroidogenic factor 1 (SF-1) plays key roles in endocrine development and function. Initially identified as a positive regulator of the cytochrome P450 steroid hydroxylases, analyses of knockout mice deficient in SF-1 revealed that SF-1 is essential for adrenal and gonadal development, pituitary gonadotropin expression and formation of the ventromedial hypothalamic nucleus. Although...

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Identifiers

PMID: 8938589
DOI: 10.1677/jme.0.0170139

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Cloning and sequence analysis of the human gene encoding steroidogenic factor 1PMID 8938589Read ↗

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