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Article

Minireview: steroidogenic factor 1: its roles in differentiation, development, and disease.

Molecular endocrinology (Baltimore, Md.) - 1 Jul 2010

Schimmer Bernard P, White Perrin C

Abstract excerpt

The orphan nuclear receptor steroidogenic factor 1 (SF-1, also called Ad4BP, encoded by the NR5A1 gene) is an essential regulator of endocrine development and function. Initially identified as a tissue-specific transcriptional regulator of cytochrome P450 steroid hydroxylases, studies of both global and tissue-specific knockout mice have demonstrated that SF-1 is required for the development of the adrenal...

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Identifiers

PMID: 20203099
DOI: 10.1210/me.2009-0519
PMCID: PMC5417463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Minireview: steroidogenic factor 1: its roles in differentiation, development, and disease.PMID 20203099Read ↗

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Steroidogenic factor-1 (SF-1, NR5A1) and human disease.Semantic proximity Read ↗

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Steroidogenic factor-1 and human disease.Semantic proximity Read ↗

Cloning and sequence analysis of the human gene encoding steroidogenic factor 1Semantic proximity Read ↗

The Orphan Nuclear Receptors Steroidogenic Factor-1 and Liver Receptor Homolog-1: Structure, Regulation, and Essential Roles in Mammalian ReproductionSemantic proximity Read ↗

SF1 in the development of the adrenal gland and gonads.Semantic proximity Read ↗

The role of steroidogenic factor 1 (SF-1) in steroidogenic cell function of the testes and ovaries of mature miceSemantic proximity Read ↗

Update--steroidogenic factor 1 (SF-1, NR5A1).Semantic proximity Read ↗

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