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Article

Cell-dependent functional roles of HIV-1 Nef for virus replication (review).

International journal of molecular medicine - 1 Apr 1999

Adachi A, Oshima Y

Abstract excerpt

The stage in the human immunodeficiency virus type 1 (HIV-1) replication cycle that is affected by Nef has been investigated. Nef is dispensable during the transcription to virion production step. In contrast, Nef is critical in the early phase of the virus replication cycle, from virion adsorption to integration. Furthermore, virions produced in the absence of Nef have been demonstrated to be inefficient to...

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Identifiers

PMID: 10085418
DOI: 10.3892/ijmm.3.4.427

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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