Effect of nef alleles on replication of human immunodeficiency virus type 1.

doi:10.1006/viro.1993.1230

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Article

Effect of nef alleles on replication of human immunodeficiency virus type 1.

Virology - 1 May 1993

Zazopoulos E, Haseltine W A

Abstract excerpt

The effect of multiple alleles of nef of the human immunodeficiency virus type 1 (HIV-1) on virus replication was examined. Nef alleles used include some derived from isolates of virus passaged in tissue culture as well as others obtained by direct cloning of viral DNA from tissues of infected patients. The effect of nef on virus replication was evaluated in the context of a derivative of the HXB2 provirus shown...

Topics

Acquired Immunodeficiency Syndrome
Alleles
Amino Acid Sequence
Animals
Base Sequence
CD4 Antigens
Cell Line
Gene Products, nef
Genes, nef
Genetic Variation
HIV-1
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Precipitin Tests

Proviruses

RNA

Sequence Homology, Amino Acid

T-Lymphocytes

Source

Open in PubMed

Identifiers

PMID: 7683154
DOI: 10.1006/viro.1993.1230

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7683154-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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