Article
C4 null alleles in childhood onset systemic lupus erythematosus. Is there any relationship with renal disease?
Pediatric nephrology (Berlin, Germany) - 1 May 1990
Clemenceau S, Castellano F, Montes de Oca M, Kaplan C, Danon F, Levy M
Abstract excerpt
C4 genotyping was performed in 38 unrelated patients with systemic lupus erythematosus (SLE) aged 2-16 years at onset. Null alleles were found in 68% of patients. Ten patients had one null allele at the C4A locus and 11 others had one null allele at the C4B locus. One patient was homozygous for C4A*Q0, 2 homozygous for C4B*Q0 and 1 heterozygous C4A*Q0/B*Q0. The last patient was C4A*Q0B*Q0/B*Q0. Three patients,...
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