Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Induction of Fas-mediated apoptosis in p53-transfected human colon carcinoma cells.

Oncogene - 16 Nov 1995

Tamura T, Aoyama N, Saya H, Haga H, Futami S, Miyamoto M, Koh T, Ariyasu T, Tachi M, Kasuga M

Abstract excerpt

To investigate the biological function of p53 in colon carcinoma cells, a wild-type p53 expression plasmid under the control of the human cytomegalovirus promoter was stably transfected into the human colon adenocarcinoma cell line WiDr, which carries a mutation of the p53 gene at codon 273. Exogenous wild-type p53 transcripts were detected at various expression levels in 8 of 117 G418-resistant clones. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Genes, p53
Share to Molecular Sequence Data

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Phenotype

Share to RNA, Messenger

Share to Signal Transduction

Share to Transfection

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 7478511

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Induction of Fas-mediated apoptosis in p53-transfected human colon carcinoma cells.PMID 7478511Read ↗

Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.Semantic proximity Read ↗

Differential involvement of the CD95 (Fas/APO-1) receptor/ligand system on apoptosis induced by the wild-type p53 gene transfer in human cancer cellsSemantic proximity Read ↗

IFN-beta induces caspase-mediated apoptosis by disrupting mitochondria in human advanced stage colon cancer cell lines.Semantic proximity Read ↗

Survivin Enhances Fas Ligand Expression via Up-Regulation of Specificity Protein 1-Mediated Gene Transcription in Colon Cancer CellsSemantic proximity Read ↗

p53 modulation of Fas/Apo-1 mediated apoptosis in a human renal cell carcinoma cell line.Semantic proximity Read ↗

Activation of the Fas pathway independently of Fas ligand during apoptosis induced by camptothecin in p53 mutant human colon carcinoma cells.Semantic proximity Read ↗

Functional interaction of wild-type and mutant p53 transfected into human tumor cell lines carrying activated ras genes.Semantic proximity Read ↗

Mechanisms of cell death induced by suicide genes encoding purine nucleoside phosphorylase and thymidine kinase in human hepatocellular carcinoma cells in vitroSemantic proximity Read ↗

Critical role for c-FLIP(L) on Fas resistance in colon carcinoma cell line HT-29.Semantic proximity Read ↗

Up-regulation of Fas (CD95) in human p53wild-type cancer cells treated with ionizing radiationSemantic proximity Read ↗

Apoptosis-prone phenotype of human colon carcinoma cells with a high level amplification of the c-myc gene.Semantic proximity Read ↗

Suppression of Human Colorectal Carcinoma Cell Growth by Wild-Type p53Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.