Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Up-regulation of Fas (CD95) in human p53wild-type cancer cells treated with ionizing radiation

27 Nov 1997

Abstract excerpt

Fas is a cell-surface protein which belongs to the tumor-necrosis-factor-receptor family. Signals through Fas are able to induce apoptosis in sensitive cells, and thus modalities for regulating the level of Fas expression on tumor cells are needed. We have studied cellular responses to gamma irradiation. The level of p53 tumor-suppressor protein was found to be elevated 3 hr after irradiation of p53wild-type...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Cancer Research and Treatments
Share to Cell death mechanisms and regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9398058
DOI: 10.1002/(sici)1097-0215(19971127)73:5<757::aid-ijc24>3.0.co;2-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Up-regulation of Fas (CD95) in human p53wild-type cancer cells treated with ionizing radiationPMID 9398058Read ↗

Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes.Semantic proximity Read ↗

p53 Activates the CD95 (APO-1/Fas) Gene in Response to DNA Damage by Anticancer DrugsSemantic proximity Read ↗

Analysis of apoptosis-related gene expression after X-ray irradiation in human tongue squamous cell carcinoma cells harboring wild-type or mutated p53 gene.Semantic proximity Read ↗

Fas is involved in the p53-dependent apoptotic response to ionizing radiation in mouse testis.Semantic proximity Read ↗

p53-dependent pathway of radio-induced apoptosis is altered in Fanconi anemia.Semantic proximity Read ↗

Distinct apoptotic phenotypes induced by radiation and ceramide in both p53-wild-type and p53-mutated lymphoblastoid cells.Semantic proximity Read ↗

Human and mouse Fas (APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis.Semantic proximity Read ↗

Role of p53 in G2/M cell cycle arrest and apoptosis in response to gamma-irradiation in ovarian carcinoma cell lines.Semantic proximity Read ↗

Apoptosis in bone marrow cells of mice with different p53 genotypes after gamma-rays irradiation in vitro.Semantic proximity Read ↗

Differential involvement of the CD95 (Fas/APO-1) receptor/ligand system on apoptosis induced by the wild-type p53 gene transfer in human cancer cellsSemantic proximity Read ↗

Resistance of MCF7 human breast carcinoma cells to TNF-induced cell death is associated with loss of p53 function.Semantic proximity Read ↗

Induction of p53 and p21 proteins by gamma radiation in skin fibroblasts derived from breast cancer patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.