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Article

Volumes of hippocampus, amygdala and frontal lobe in Alzheimer patients with different apolipoprotein E genotypes.

Neuroscience - 1 Jul 1995

Lehtovirta M, Laakso M P, Soininen H, Helisalmi S, Mannermaa A, Helkala E L, Partanen K, Ryynänen M, Vainio P, Hartikainen P

Abstract excerpt

An increased frequency of apolipoprotein E E4 allele has been reported in patients with late onset Alzheimer's disease. Apolipoprotein E participates in the transport of cholesterol and other lipids and interferes with the growth and regeneration of both peripheral and central nervous system tissues during development and after injury. Apolipoprotein E is also implicated in synaptogenesis. Apolipoprotein E...

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Identifiers

PMID: 7477910
DOI: 10.1016/0306-4522(95)00014-a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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