Article
Clinical features and alterations in the inferior horn sizes in lateral ventricle in Alzheimer's patients with different ApoE genotype in Japanese population.
Progress in neuro-psychopharmacology & biological psychiatry - 1 Oct 2001
Yoshida S, Iwabuchi Y, Numachi Y, Saito H, Yamazaki H, Sakai H, Kimura M, Matsuoka H, Sato M
Abstract excerpt
E4 allele of Apolipoprotein E (ApoE) is considered to be not only a risk factor for Alzheimer's disease (AD) but also a determinant of clinical features in AD. However, it is still controversial whether ApoE e4 allele is related to age at onset, severity of memory impairment or brain morphological changes in AD patients. The present study examined the issue in Japanese population: 1) ApoE genotype on in 38 normal...
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