Article
A stomatin-domain protein essential for touch sensation in the mouse.
Nature - 11 Jan 2007
Wetzel Christiane, Hu Jing, Riethmacher Dieter, Benckendorff Anne, Harder Lena, Eilers Andreas, Moshourab Rabih, Kozlenkov Alexey, Labuz Dominika, Caspani Ombretta, Erdmann Bettina, Machelska Halina, Heppenstall Paul A, Lewin Gary R
Abstract excerpt
Touch and mechanical pain are first detected at our largest sensory surface, the skin. The cell bodies of sensory neurons that detect such stimuli are located in the dorsal root ganglia, and subtypes of these neurons are specialized to detect specific modalities of mechanical stimuli. Molecules have been identified that are necessary for mechanosensation in invertebrates but so far not in mammals. In...
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