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Article

Natural selection on the gag, pol, and env genes of human immunodeficiency virus 1 (HIV-1).

Molecular biology and evolution - 1 Sept 1995

Seibert S A, Howell C Y, Hughes M K, Hughes A L

Abstract excerpt

Natural selection on polymorphic protein-coding loci of human immunodeficiency virus-1 (HIV-1), the more geographically widespread of the two viruses causing human acquired immune deficiency syndrome (AIDS), was studied by estimating the rates of nucleotide substitution per site in comparisons among alleles classified in families of related alleles on the basis of a phylogenetic analysis. In the case of gag, pol,...

Topics

Acquired Immunodeficiency Syndrome
Alleles
Amino Acid Sequence
Epitopes
Genes, env
Genes, gag
Genes, pol
HIV Envelope Protein gp120
HIV Envelope Protein gp41
HIV-1
HIV-2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Molecular Sequence Data

Phylogeny

Selection, Genetic

T-Lymphocytes

Source

Identifiers

PMID: 7476126
DOI: 10.1093/oxfordjournals.molbev.a040257

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7476126-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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