Processing of the envelope glycoprotein gp160 in immunotoxin-resistant cell lines chronically infected with human immunodeficiency virus type 1.

doi:10.1128/JVI.69.11.7122-7131.1995

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Article

Processing of the envelope glycoprotein gp160 in immunotoxin-resistant cell lines chronically infected with human immunodeficiency virus type 1.

Journal of virology - 1 Nov 1995

Duensing T D, Fang H, Dorward D W, Pincus S H

Abstract excerpt

We describe the isolation and characterization of variant cell lines which are chronically infected with the human immunodeficiency virus (HIV) and resistant to the action of immunotoxins directed against the HIV envelope protein. These variants all produce normal levels of HIV proteins, budding virions, and the envelope protein precursor gp160. Two of the variants, 10E and 11E, contain a mutation within the env...

Topics

Antigens, CD
CD4 Antigens
Cell Division
Cell Line
Dose-Response Relationship, Drug
Drug Resistance
Gene Products, env
Genes, env
Genetic Variation
HIV Envelope Protein gp160
HIV-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HeLa Cells

Humans

Immunotoxins

Microscopy, Electron, Scanning

Protein Precursors

Protein Processing, Post-Translational

RNA, Messenger

Source

Open in PubMed Open full text

Identifiers

PMID: 7474132
DOI: 10.1128/JVI.69.11.7122-7131.1995
PMCID: PMC189632

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7474132-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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