Article

Characterization of full-length and cytoplasmic tail-truncated envelope glycoproteins incorporated into human immunodeficiency virus (HIV-1) virions and virus-like particles

2025-07-10

Abstract excerpt

<h4>ABSTRACT</h4> During transport to the surface of infected cells, the human immunodeficiency virus (HIV-1) envelope glycoprotein (Env) trimer is cleaved to produce the mature functional Env trimer ((gp120/gp41) 3 ). Env cleavage stabilizes the pretriggered Env conformation (PTC), the major target for broadly neutralizing antibodies. Although the mature Env is relatively enriched in virions and virus-like part...

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Literature Corpus work: a377c2db-307c-55ec-bc31-c46c7fb1f015
DOI: 10.1101/2025.07.10.664145

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