Article
The multi-ion nature of the cGMP-gated channel from vertebrate rods.
The Journal of physiology - 15 Aug 1995
Sesti F, Eismann E, Kaupp U B, Nizzari M, Torre V
Abstract excerpt
1. Native cGMP-gated channels were studied in rod outer segments of the larval tiger salamander, Ambystoma tigrinum. The alpha-subunit of the cGMP-gated channel, here referred to as the wild type (WT), and mutant channels were heterologously expressed in Xenopus laevis oocytes. These channels were studied in excised membrane patches in the inside-out configuration and were activated by the addition of 100 or 500...
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