Article
Role in cation translocation of the N-terminus of the alpha-subunit of the Na(+)-K+ pump of Bufo.
The Journal of physiology - 15 Mar 1996
Wang X, Jaisser F, Horisberger J D
Abstract excerpt
1. We have studied the effects on the physiological properties of the Na(+)-K+ pump of both 31- and 40-amino acid N-terminal truncated forms of the alpha-subunit of the Na(+)-K(+)-ATPase. 2. Na(+)-K+ pumps that were moderately ouabain resistant (K1 = 50 microM) were expressed in the Xenopus oocyte by injection of wild-type or truncated variants of the Bufo marinus Na(+)-K(+)-ATPase alpha-subunit cRNA with Bufo...
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