Article
Effect of ultraviolet light on DNA replication in excision-deficient mammalian cells.
Mutation research - 1 Jan 2000
Griffiths T D, Ling S Y
Abstract excerpt
DNA replication after exposure to 254-nm ultraviolet light was examined in wild-type (AA8) and excision-deficient (UV-5) Chinese hamster ovary (CHO) cells. DNA replication was examined by measuring the incorporation of [3H]thymidine into acid-precipitable form and by DNA fiber autoradiography. Following exposure to UV both cell lines exhibited a fluence-dependent reduction in the rate of incorporation of...
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