Effect of UV light on DNA chain growth and replicon initiation in xeroderma pigmentosum variant cells.

doi:10.1093/mutage/6.4.247

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Article

Effect of UV light on DNA chain growth and replicon initiation in xeroderma pigmentosum variant cells.

Mutagenesis - 1 Jul 1991

Griffiths T D, Ling S Y

Abstract excerpt

The effects of UV light on DNA replication were examined in wild-type and xeroderma pigmentosum (XP) variant cells using DNA fiber autoradiography. Replication segments were significantly shorter in UV-exposed XP variant cells than they were in UV-exposed wild-type human cells immediately after e...

Topics

Animals
Cell Line
DNA Repair
DNA Replication
Fibroblasts
Humans
Phenotype
Replicon
Ultraviolet Rays
Xeroderma Pigmentosum

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