Hybrid HLA-DC antigens provide molecular evidence for gene trans-complementation.

doi:10.1038/312157a0

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Article

Hybrid HLA-DC antigens provide molecular evidence for gene trans-complementation.

Nature - 1 Jan 2000

Charron D J, Lotteau V, Turmel P

Abstract excerpt

In the mouse there are hybrid determinants for the immune region (Ir) of the genome which contribute to the diversity of class II (Ia) antigens of the major histocompatibility complex (MHC) and provide a molecular basis for Ir gene complementation. In man, two prominent families of Ia molecule, H...

Topics

Animals
Antibodies, Monoclonal
Cell Line
Epitopes
Genes
Genetic Complementation Test
Genetic Variation
HLA-DQ Antigens
Histocompatibility Antigens Class II
Mice
Protein Multimerization

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