Article
Genetic and molecular definition of complementation group D in MHC class II deficiency.
Human molecular genetics - 1 May 1998
Fondaneche M C, Villard J, Wiszniewski W, Jouanguy E, Etzioni A, Le Deist F, Peijnenburg A, Casanova J L, Reith W, Mach B, Fischer A, Lisowska-Grospierre B
Abstract excerpt
Four complementation groups, A, B, C and D, have been described among cell lines defective in the coordinate expression of MHC class II genes. These include cell lines established from patients affected with MHC class II deficiency and experimentally generated mutant cell lines. Group D, in contr...
Topics
- Antigens, Differentiation, B-Lymphocyte
- B-Lymphocytes
- Cell Line
- DNA-Binding Proteins
- Fibroblasts
- Gene Expression
- Genes, MHC Class II
- Genetic Complementation Test
- HLA-D Antigens
- Histocompatibility Antigens Class II
- Humans
- Mutation
- Regulatory Factor X Transcription Factors
- Transfection